MDD 93/42/EEC自1998年12月7日颁布以来，根据法规的实施情况、社会的发展和科技的进步共进行5次修改，其修改历史如下：
?M1Directive 98/79/EC of the European Parliament and of the Council of 27 October 1998
?M2Directive 2000/70/EC of the European Parliament and of the Council of 16 November 2000
?M3Directive 2001/104/EC of the European Parliament and of the Council of 7 December 2001
?M4Regulation (EC) No 1882/2003 of the European Parliament and of the Council of 29 September 2003
?M5Directive 2007/47/EC of the European Parliament and of the Council of 5 September 2007